OR24-4 Homeostatic and Tumourigenic Activity of SOX2+ Pituitary Stem Cells is Controlled by the LATS/YAP/TAZ Cascade

SOX2 positive pituitary stem cells (PSCs) are specified during embryonic development and persist throughout life, giving rise to all anterior pituitary endocrine lineages. We have previously revealed the activation of the LATS/YAP/TAZ signaling cascade in the developing and postnatal mammalian pitui...

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Detalles Bibliográficos
Autores principales: Lodge, Emily, Santambrogio, Alice, Russell, John, Bornstein, Stefan, Andoniadou, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554787/
http://dx.doi.org/10.1210/js.2019-OR24-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554787/
http://dx.doi.org/10.1210/js.2019-OR24-4

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