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OR24-4 Homeostatic and Tumourigenic Activity of SOX2+ Pituitary Stem Cells is Controlled by the LATS/YAP/TAZ Cascade
SOX2 positive pituitary stem cells (PSCs) are specified during embryonic development and persist throughout life, giving rise to all anterior pituitary endocrine lineages. We have previously revealed the activation of the LATS/YAP/TAZ signaling cascade in the developing and postnatal mammalian pitui...
Autores principales: | Lodge, Emily, Santambrogio, Alice, Russell, John, Bornstein, Stefan, Andoniadou, Cynthia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554787/ http://dx.doi.org/10.1210/js.2019-OR24-4 |
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