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OR09-6 Selective and Durable Suppression of Aldosterone Production in Non-Human Primates by a Novel Aldosterone Synthase Inhibitor

Primary aldosteronism (PA) is a common form of secondary hypertension driven by the autonomous production of aldosterone. Often described as low-renin hypertension, PA is a major public health concern given its prevalence and associated cardiovascular and renal pathology. Compared to patients with e...

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Detalles Bibliográficos
Autores principales: Sparks, Steven, Garvey, Edward, Hoekstra, William, Schotzinger, Robert, Becherer, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554804/
http://dx.doi.org/10.1210/js.2019-OR09-6