Cargando…
OR09-6 Selective and Durable Suppression of Aldosterone Production in Non-Human Primates by a Novel Aldosterone Synthase Inhibitor
Primary aldosteronism (PA) is a common form of secondary hypertension driven by the autonomous production of aldosterone. Often described as low-renin hypertension, PA is a major public health concern given its prevalence and associated cardiovascular and renal pathology. Compared to patients with e...
Autores principales: | Sparks, Steven, Garvey, Edward, Hoekstra, William, Schotzinger, Robert, Becherer, J. David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554804/ http://dx.doi.org/10.1210/js.2019-OR09-6 |
Ejemplares similares
-
OR09-05 Expression of SLC35F1 in the Plasma Membrane of Cells of Aldosterone Producing Cell Clusters (APCCs) and Its Possible Role in Aldosterone Synthesis
por: Goodchild, Emily, et al.
Publicado: (2020) -
SAT-016 The Influence of Aldosterone Values in the Tributary Veins of Unresected Adrenal Gland on Primary Aldosteronism Surgical Outcomes
por: Nakai, Kazuki, et al.
Publicado: (2019) -
SAT-012 Urinary Aldosterone Assay Using LC-MS/MS Could Improve Primary Aldosteronism Screening
por: Travers, Simon, et al.
Publicado: (2019) -
RNA-Binding Protein Musashi-2 Inhibits Aldosterone Production
por: Bartholomay, Kathryn, et al.
Publicado: (2021) -
LBMON299 Aldosterone Production Is Regulated By Gap Junctions In Human Adrenal Cells
por: Goodchild, Emily, et al.
Publicado: (2022)