OR05-5 AZP-3404, a 9-Amino Acid Peptide Analog of Insulin-Like Growth Factor-Binding Protein 2, Reverses Insulin Resistance in Leptin-Deficient ob/ob Mice

Insulin-like growth factor-binding protein-2 (IGFBP-2), one of six highly-conserved binding proteins that modulate circulating IGF1, has significant regulatory actions on carbohydrate, lipid and bone metabolism that are independent of its IGF-1 binding role. The metabolic activity of IGFBP-2 has bee...

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Detalles Bibliográficos
Autores principales: Milano, Stephane, Delale, Thomas, Abribat, Thierry, Culler, Michael, van der Lely, Aart, Clemmons, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554832/
http://dx.doi.org/10.1210/js.2019-OR05-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554832/
http://dx.doi.org/10.1210/js.2019-OR05-5

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