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OR28-2 The Ldb1 Transcriptional Co-regulator Is Required for Establishment, Development, and Survival of the Pancreatic Endocrine Lineage

Pancreatic islets are comprised of hormone-secreting cell types that are vital regulators of glucose homeostasis. Specifically, the pancreatic β-cell is indispensable for glucose metabolism and its dysfunction is central to diabetes mellitus. β-cell development is regulated by transcription factor (...

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Detalles Bibliográficos
Autores principales: Toren, Eliana, Liu, Yanping, Hunter, Chad, Bethea, Maigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554838/
http://dx.doi.org/10.1210/js.2019-OR28-2