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OR28-2 The Ldb1 Transcriptional Co-regulator Is Required for Establishment, Development, and Survival of the Pancreatic Endocrine Lineage
Pancreatic islets are comprised of hormone-secreting cell types that are vital regulators of glucose homeostasis. Specifically, the pancreatic β-cell is indispensable for glucose metabolism and its dysfunction is central to diabetes mellitus. β-cell development is regulated by transcription factor (...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554838/ http://dx.doi.org/10.1210/js.2019-OR28-2 |