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OR02-2 CX-4945 as a Potential Drug for Adrenocortical Carcinoma That Induces Multiple Exon-Skipping and Circular RNA of NR5A1

Orphan nuclear receptor NR5A1 (also called adrenal 4-binding protein/steroidogenic factor-1) is the major regulator of differentiation and function of the adrenal cortex. Adrenocortical carcinoma is rare and deadly with few therapeutic options and is known to have the tendency of increased NR5A1expr...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomoko, Ohe, Kenji, Nomiyama, Takashi, Yanase, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554865/
http://dx.doi.org/10.1210/js.2019-OR02-2