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The effects of a hirudin/liposome complex on a diabetic nephropathy rat model

BACKGROUND: Hirudin, an extract from Hirudo spp., is an anticoagulant used to treat a variety of renal diseases, including diabetic nephropathy (DN). Currently, hirudin has to be used at high dosages to treat DN because it poorly targets the kidneys, although at high dosages it can have severe side...

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Detalles Bibliográficos
Autores principales: Wang, Hongwu, Cui, Huantian, Lin, Lan, Ji, Yue, Ni, Qing, Li, Junchen, Pang, Jianli, Bing, Gongyan, Bian, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554961/
https://www.ncbi.nlm.nih.gov/pubmed/31170978
http://dx.doi.org/10.1186/s12906-019-2531-7