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The effects of a hirudin/liposome complex on a diabetic nephropathy rat model
BACKGROUND: Hirudin, an extract from Hirudo spp., is an anticoagulant used to treat a variety of renal diseases, including diabetic nephropathy (DN). Currently, hirudin has to be used at high dosages to treat DN because it poorly targets the kidneys, although at high dosages it can have severe side...
Autores principales: | Wang, Hongwu, Cui, Huantian, Lin, Lan, Ji, Yue, Ni, Qing, Li, Junchen, Pang, Jianli, Bing, Gongyan, Bian, Yuhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554961/ https://www.ncbi.nlm.nih.gov/pubmed/31170978 http://dx.doi.org/10.1186/s12906-019-2531-7 |
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