NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer

BACKGROUND: Temozolomide-perillyl alcohol conjugate (NEO212), a novel temozolomide (TMZ) analog, was previously reported to exert its anti-cancer effect in non-small cell lung cancer (NSCLC), and human nasopharyngeal carcinoma (NPC), etc.. In the current study, we intend to illuminate the potential...

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Detalles Bibliográficos
Autores principales: Song, Xingguo, Liu, Lisheng, Chang, Minghui, Geng, Xinran, Wang, Xingwu, Wang, Weijun, Chen, Thomas C., Xie, Li, Song, Xianrang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554966/
https://www.ncbi.nlm.nih.gov/pubmed/31174569
http://dx.doi.org/10.1186/s13046-019-1249-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554966/
https://www.ncbi.nlm.nih.gov/pubmed/31174569
http://dx.doi.org/10.1186/s13046-019-1249-1

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