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β-Catenin nuclear localization positively feeds back on EGF/EGFR-attenuated AJAP1 expression in breast cancer

BACKGROUND: Adherent junction associated protein 1 (AJAP1), a typical molecule of adherent junctions, has been found to be a tumor suppressor in many cancer types. Aberrant activation of β-catenin has been demonstrated to be associated with malignant biological properties of tumors including breast...

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Detalles Bibliográficos
Autores principales: Xu, Cong, Liu, Fang, Xiang, Guomin, Cao, Lu, Wang, Shuling, Liu, Jing, Meng, Qingxiang, Xu, Danni, Lv, Shuhua, Jiao, Jiao, Niu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554977/
https://www.ncbi.nlm.nih.gov/pubmed/31171012
http://dx.doi.org/10.1186/s13046-019-1252-6