Vaccination with synthetic long peptide formulated with CpG in an oil-in-water emulsion induces robust E7-specific CD8 T cell responses and TC-1 tumor eradication

BACKGROUND: Despite considerable efforts at developing therapeutic vaccines for cancer, clinical translation of preclinical successes has been challenging, largely due to the difficulty of inducing strong and sustained cytotoxic T lymphocyte (CTL) responses in patients. Several peptide-based cancer...

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Detalles Bibliográficos
Autores principales: Maynard, Sean K., Marshall, Jason D., MacGill, Randall S., Yu, Li, Cann, Jennifer A., Cheng, Lily I., McCarthy, Michael P., Cayatte, Corinne, Robbins, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555006/
https://www.ncbi.nlm.nih.gov/pubmed/31170937
http://dx.doi.org/10.1186/s12885-019-5725-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555006/
https://www.ncbi.nlm.nih.gov/pubmed/31170937
http://dx.doi.org/10.1186/s12885-019-5725-y

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