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OR04-2 Aldosterone Induces Trained Immunity via Fatty Acid Synthesis

Hyperaldosteronism is associated with an increased cardiovascular risk in humans. Animal models show that aldosterone accelerates the development of atherosclerotic plaques, and suggest that this is, at least in part, mediated by activation of innate immune cells by aldosterone (1). Human data are s...

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Detalles Bibliográficos
Autores principales: van der Heijden, Charlotte, Keating, Samuel, Groh, Laszlo, Smeets, Esther, Aarntzen, Erik, Joosten, Leo, Netea, Mihai, Riksen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555016/
http://dx.doi.org/10.1210/js.2019-OR04-2