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Intranasal administration with recombinant Bacillus subtilis induces strong mucosal immune responses against pseudorabies
BACKGROUND: Pseudorabies caused by pseudorabies virus (PRV) mainly infects the swine and seriously threatens the biosafety of the other animals, including humans. Since 2011, the outbreaks of PRV mutants have caused enormous economic losses in the swine industry, and traditional vaccines cannot offe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555017/ https://www.ncbi.nlm.nih.gov/pubmed/31170996 http://dx.doi.org/10.1186/s12934-019-1151-8 |