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OR15-2 A Novel Upstream Enhancer Acts Synergistically with GnRH and Activin to Increase FSHβ Transcription

Polycystic ovary syndrome (PCOS) is the most common cause of female infertility and is associated with an increased risk of type 2 diabetes and cardiovascular disease. Understanding the etiology of PCOS is crucial to relieve this tremendous health burden. Twin studies estimate that 70% of PCOS etiol...

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Detalles Bibliográficos
Autores principales: Bohaczuk, Stephanie, Thackray, Varykina, Mellon, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555018/
http://dx.doi.org/10.1210/js.2019-OR15-2