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OR26-5 Functional Analysis of Estrogen-Regulated Enhancer RNAs in Breast Cancer Cells

Approximately 70% of breast cancers express estrogen receptor alpha (ERα), a hormone-regulated transcription factor, making it an excellent target for endocrine therapy. When endogenous and exogenous ligands engage ERα, the receptor binds to regulatory regions in the genome known as enhancers, where...

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Detalles Bibliográficos
Autores principales: Hou, Tim, Malladi, Venkat, Nagari, Anusha, Kraus, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555046/
http://dx.doi.org/10.1210/js.2019-OR26-5