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OR31-3 Role of a Novel Short Chain Fatty Acid Receptor OLFR78 in Mediating Gluco-metabolic Hormone Secretion

Olfactory receptor OLFR78 is a G protein-coupled receptor (GPCR) which is activated by short chain fatty acids (SCFAs), especially propionate. OLFR78 is expressed in islets as well as intestinal epithelial cells. Based on these properties, we hypothesized its role in the regulation of metabolic horm...

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Detalles Bibliográficos
Autores principales: Lednovich, Kristen, Priyadarshini, Medha, Kotlo, Kumar, Xu, Kai, Priyamvada, Shubha, Dudeja, Pradeep, Layden, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555068/
http://dx.doi.org/10.1210/js.2019-OR31-3