OR05-6 The Effect of the GLP1R Variant rs6923761 on Post-Prandial Glucose Levels during Treatment with Sitagliptin

BACKGROUND: Glucagon-like peptide-1 (GLP-1) functions to increase insulin production in a glucose-dependent manner. Endogenous GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase 4 (DPP4), and GLP-1 receptor agonists and DPP4 inhibitors (DPP4Is) are now used in the treatment of diabetes. Th...

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Detalles Bibliográficos
Autores principales: Mashayekhi, Mona, Wilson, Jessica, Jafarian-Kerman, Scott, Brown, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555090/
http://dx.doi.org/10.1210/js.2019-OR05-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555090/
http://dx.doi.org/10.1210/js.2019-OR05-6

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