Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency

Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with a combination of epigenomic modifiers and signaling molecu...

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Detalles Bibliográficos
Autores principales: Tran, Khoa A., Pietrzak, Stefan J., Zaidan, Nur Zafirah, Siahpirani, Alireza Fotuhi, McCalla, Sunnie Grace, Zhou, Amber S., Iyer, Gopal, Roy, Sushmita, Sridharan, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555151/
https://www.ncbi.nlm.nih.gov/pubmed/31067459
http://dx.doi.org/10.1016/j.celrep.2019.04.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555151/
https://www.ncbi.nlm.nih.gov/pubmed/31067459
http://dx.doi.org/10.1016/j.celrep.2019.04.056

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