Cargando…

Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency

Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with a combination of epigenomic modifiers and signaling molecu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tran, Khoa A., Pietrzak, Stefan J., Zaidan, Nur Zafirah, Siahpirani, Alireza Fotuhi, McCalla, Sunnie Grace, Zhou, Amber S., Iyer, Gopal, Roy, Sushmita, Sridharan, Rupa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555151/ https://www.ncbi.nlm.nih.gov/pubmed/31067459 http://dx.doi.org/10.1016/j.celrep.2019.04.056

Ejemplares similares

Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets
por: Zhang, Shilu, et al.
Publicado: (2023)

Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage
por: Jackson, Steven A., et al.
Publicado: (2016)

Identifying strengths and weaknesses of methods for computational network inference from single-cell RNA-seq data
por: McCalla, Sunnie Grace, et al.
Publicado: (2023)

HP1γ regulates H3K36 methylation and pluripotency in embryonic stem cells
por: Zaidan, Nur Zafirah, et al.
Publicado: (2020)

Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways
por: Tran, Khoa A., et al.
Publicado: (2015)

Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance
por: Zaidan, Nur Zafirah, et al.
Publicado: (2018)

A predictive modeling approach for cell line-specific long-range regulatory interactions
por: Roy, Sushmita, et al.
Publicado: (2016)

A predictive modeling approach for cell line-specific long-range regulatory interactions
por: Roy, Sushmita, et al.
Publicado: (2015)

Dynamic regulatory module networks for inference of cell type–specific transcriptional networks
por: Siahpirani, Alireza Fotuhi, et al.
Publicado: (2022)

A multi-task graph-clustering approach for chromosome conformation capture data sets identifies conserved modules of chromosomal interactions
por: Fotuhi Siahpirani, Alireza, et al.
Publicado: (2016)

A Pan-Cancer Modular Regulatory Network Analysis to Identify Common and Cancer-Specific Network Components
por: Knaack, Sara A, et al.
Publicado: (2014)

Modular derivation of diverse, regionally discrete human posterior CNS neurons enables discovery of transcriptomic patterns
por: Iyer, Nisha R., et al.
Publicado: (2022)

The complete mitochondrial genome of Hine’s emerald dragonfly (Somatochlora hineana Williamson) via NGS sequencing
por: Jackson, Craig, et al.
Publicado: (2018)

DOT1L is a barrier to histone acetylation during reprogramming to pluripotency
por: Wille, Coral K., et al.
Publicado: (2023)

A prior-based integrative framework for functional transcriptional regulatory network inference
por: Siahpirani, Alireza F., et al.
Publicado: (2017)

A prior-based integrative framework for functional transcriptional regulatory network inference
por: Siahpirani, Alireza F., et al.
Publicado: (2017)

Defining the Pluripotent Marker Genes for Identification of Teleost Fish Cell Pluripotency During Reprogramming
por: Li, Huajin, et al.
Publicado: (2022)

Imputed gene associations identify replicable trans‐acting genes enriched in transcription pathways and complex traits
por: Wheeler, Heather E., et al.
Publicado: (2019)

A Thesis on Tic Douloureux, or Neuralgia Faciei
por: McCalla, John
Publicado: (1848)

On Filing Teeth for Superficial Decay
por: McCalla, Jno.
Publicado: (1860)

Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes
por: Roy, Sushmita, et al.
Publicado: (2017)

In Vivo Cell Reprogramming towards Pluripotency by Virus-Free Overexpression of Defined Factors
por: Yilmazer, Açelya, et al.
Publicado: (2013)

Fast and Efficient Mouse Pluripotency Reprogramming Using a Chemically-Defined Medium
por: Huang, Junju, et al.
Publicado: (2022)

Transcriptome-wide transmission disequilibrium analysis identifies novel risk genes for autism spectrum disorder
por: Huang, Kunling, et al.
Publicado: (2021)

Lógica digital y diseño de computadoras /
por: McCalla, Thomas Richard
Publicado: (1994)

Twentieth-century chamber music /
por: McCalla, James 1946-
Publicado: (2003)

Introduction to numerical methods and FORTRAN programming
por: McCalla, Thomas Richard
Publicado: (1967)

Ti-84 Plus graphing calculator for dummies
por: McCalla, et al.
Publicado: (2013)

DOT1L inhibition enhances pluripotency beyond acquisition of epithelial identity and without immediate suppression of the somatic transcriptome
por: Wille, Coral K., et al.
Publicado: (2022)

Proteomic and genomic approaches reveal critical functions of H3K9 methylation and Heterochromatin Protein-1γ in reprogramming to pluripotency
por: Sridharan, Rupa, et al.
Publicado: (2013)

Molecular mechanisms of pluripotency and reprogramming
por: Na, Jie, et al.
Publicado: (2010)

Linking Pluripotency Reprogramming and Cancer
por: Iglesias, Juan Manuel, et al.
Publicado: (2016)

Reprogramming of Sheep Fibroblasts into Pluripotency under a Drug-Inducible Expression of Mouse-Derived Defined Factors
por: Li, Yang, et al.
Publicado: (2011)

Prophet forecasting model: a machine learning approach to predict the concentration of air pollutants (PM(2.5), PM(10), O(3), NO(2), SO(2), CO) in Seoul, South Korea
por: Shen, Justin, et al.
Publicado: (2020)

Detection and Classification of Immature Leukocytes for Diagnosis of Acute Myeloid Leukemia Using Random Forest Algorithm
por: Dasariraju, Satvik, et al.
Publicado: (2020)

Detecting the movement and spawning activity of bigheaded carps with environmental DNA
por: Erickson, Richard A., et al.
Publicado: (2016)

Conservative Management of Cesarean Scar Ectopic Pregnancy with Fetal Heart Activity and a Very High β-hCG
por: McLaren, Rodney, et al.
Publicado: (2015)

Human pluripotent reprogramming with CRISPR activators
por: Weltner, Jere, et al.
Publicado: (2018)

Somatic Reprogramming—Above and Beyond Pluripotency
por: Meir, Yaa-Jyuhn James, et al.
Publicado: (2021)

Enhanced Expansion of Human Pluripotent Stem Cells and Somatic Cell Reprogramming Using Defined and Xeno-Free Culture Conditions
por: Timilsina, Suraj, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_beqep5qgq8d9bufs7h89p9c4p6