Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9

Clustered regularly interspaced short palindromic repeat (CRISPR) RNAs and their associated effector (Cas) enzymes are being developed into promising therapeutics to treat disease. However, CRISPR-Cas enzymes might produce unwanted gene editing or dangerous side effects. Drug-like molecules that can...

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Detalles Bibliográficos
Autores principales: Barkau, Christopher L., O'Reilly, Daniel, Rohilla, Kushal J., Damha, Masad J., Gagnon, Keith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555185/
https://www.ncbi.nlm.nih.gov/pubmed/30990769
http://dx.doi.org/10.1089/nat.2018.0758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555185/
https://www.ncbi.nlm.nih.gov/pubmed/30990769
http://dx.doi.org/10.1089/nat.2018.0758

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