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Gradient Boosting Decision Tree-Based Method for Predicting Interactions Between Target Genes and Drugs

Determining the target genes that interact with drugs—drug–target interactions—plays an important role in drug discovery. Identification of drug–target interactions through biological experiments is time consuming, laborious, and costly. Therefore, using computational approaches to predict candidate...

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Detalles Bibliográficos
Autores principales: Xuan, Ping, Sun, Chang, Zhang, Tiangang, Ye, Yilin, Shen, Tonghui, Dong, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555260/
https://www.ncbi.nlm.nih.gov/pubmed/31214240
http://dx.doi.org/10.3389/fgene.2019.00459