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Phosphorylation of the Archaeal Holliday Junction Resolvase Hjc Inhibits Its Catalytic Activity and Facilitates DNA Repair in Sulfolobus islandicus REY15A

Protein phosphorylation is one of the main protein post-translational modifications and regulates DNA repair in eukaryotes. Archaeal genomes encode eukaryotic-like DNA repair proteins and protein kinases (ePKs), and several proteins involved in homologous recombination repair (HRR) including Hjc, a...

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Detalles Bibliográficos
Autores principales: Huang, Qihong, Mayaka, Joseph Badys, Zhong, Qing, Zhang, Chao, Hou, Guihua, Ni, Jinfeng, Shen, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555300/
https://www.ncbi.nlm.nih.gov/pubmed/31214148
http://dx.doi.org/10.3389/fmicb.2019.01214