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Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells

Many infertile women suffered from poor ovarian response, and increased reactive oxygen species with age might mediate the poor ovarian response to FSH. In this study, we collected follicular fluids and isolated granulosa cells from female patients. Increased levels of peroxynitrite, tyrosine nitrat...

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Detalles Bibliográficos
Autores principales: Zhou, Ge, Hu, Rong-kui, Xia, Gui-cheng, Yan, Shi-hai, Ren, Qing-ling, Zhao, Juan, Wang, Fei-hong, Huang, Cheng-cai, Yao, Qi, Tan, Yong, Zhao, Ning-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555443/
https://www.ncbi.nlm.nih.gov/pubmed/31097679
http://dx.doi.org/10.18632/aging.101964