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Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells
Many infertile women suffered from poor ovarian response, and increased reactive oxygen species with age might mediate the poor ovarian response to FSH. In this study, we collected follicular fluids and isolated granulosa cells from female patients. Increased levels of peroxynitrite, tyrosine nitrat...
Autores principales: | Zhou, Ge, Hu, Rong-kui, Xia, Gui-cheng, Yan, Shi-hai, Ren, Qing-ling, Zhao, Juan, Wang, Fei-hong, Huang, Cheng-cai, Yao, Qi, Tan, Yong, Zhao, Ning-wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555443/ https://www.ncbi.nlm.nih.gov/pubmed/31097679 http://dx.doi.org/10.18632/aging.101964 |
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