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circFADS2 protects LPS-treated chondrocytes from apoptosis acting as an interceptor of miR-498/mTOR cross-talking

We aimed to investigate the regulation of circular RNAs in lipopolysaccharide (LPS)-treated chondrocytes isolated from SD rat. In this study, we analyzed how circFADS2 was regulated in LPS-treated chondrocytes and isolates from Rheumatoid arthritis (RA) patients and found that circFADS2 and mTOR wer...

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Detalles Bibliográficos
Autores principales: Li, Guoqing, Tan, Wei, Fang, Yuxuan, Wu, Xia, Zhou, Wei, Zhang, Chunwang, Zhang, Yu, Liu, Yanqing, Jiu, Guangzheng, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555446/
https://www.ncbi.nlm.nih.gov/pubmed/31141496
http://dx.doi.org/10.18632/aging.101986