Cargando…

Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation

The advent of epigenetic clocks has prompted questions about the place of epigenetic ageing within the current understanding of ageing biology. It was hitherto unclear whether epigenetic ageing represents a distinct mode of ageing or a manifestation of a known characteristic of ageing. We report her...

Descripción completa

Detalles Bibliográficos
Autores principales: Horvath, Steve, Lu, Ake T., Cohen, Howard, Raj, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555449/
https://www.ncbi.nlm.nih.gov/pubmed/31136303
http://dx.doi.org/10.18632/aging.101976