Simvastatin induces breast cancer cell death through oxidative stress up-regulating miR-140-5p

Statins, a class of hyperlipidemic drugs, are widely used cholesterol lowering drugs that selectively inhibit 3-hydroxy-3-methylglutaryl CoA reductase, which is the rate-limiting enzyme in cholesterol biosynthesis, leading to decreasing of cholesterol biosynthesis. Statins exert anti-tumoral effects...

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Detalles Bibliográficos
Autores principales: Bai, Fuliang, Yu, Ze, Gao, Xin, Gong, Jiawei, Fan, Lizhi, Liu, Feifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555469/
https://www.ncbi.nlm.nih.gov/pubmed/31138773
http://dx.doi.org/10.18632/aging.101974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555469/
https://www.ncbi.nlm.nih.gov/pubmed/31138773
http://dx.doi.org/10.18632/aging.101974

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