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Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice

Neurodegenerative diseases associated with old age such as Alzheimer’s disease present major problems for society, and they currently have no cure. The telomere protective caps at the ends of chromosomes shorten with age, and when they become critically short, they can induce a persistent DNA damage...

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Detalles Bibliográficos
Autores principales: Whittemore, Kurt, Derevyanko, Aksinya, Martinez, Paula, Serrano, Rosa, Pumarola, Martí, Bosch, Fàtima, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555470/
https://www.ncbi.nlm.nih.gov/pubmed/31140977
http://dx.doi.org/10.18632/aging.101982