Brain-specific NRSF deficiency aggravates dopaminergic neurodegeneration and impairs neurogenesis in the MPTP mouse model of Parkinson’s disease

Degeneration of the dopaminergic neurons in the substantia nigra and the resultant dopamine depletion from the striatum are the hallmarks of Parkinson’s disease (PD) and are responsible for the disease’s cardinal motor symptoms. The transcriptional repressor Neuron-Restrictive Silencer Factor (NRSF)...

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Detalles Bibliográficos
Autores principales: Huang, Dongping, Li, Qing, Wang, Yi, Liu, Zhaolin, Wang, Zishan, Li, Heng, Wang, Jinghui, Su, Jing, Ma, Yuanyuan, Yu, Mei, Fei, Jian, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555471/
https://www.ncbi.nlm.nih.gov/pubmed/31147527
http://dx.doi.org/10.18632/aging.101979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555471/
https://www.ncbi.nlm.nih.gov/pubmed/31147527
http://dx.doi.org/10.18632/aging.101979

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