Upregulation of sphingosine-1-phosphate receptor 3 on fibroblast-like synoviocytes is associated with the development of collagen-induced arthritis via increased interleukin-6 production

BACKGROUND: Sphingosine-1-phosphate receptor 3 (S1P(3)) is one of five receptors for sphingosine-1-phosphate (S1P). S1P/S1P(3) signaling is involved in numerous physiological and pathological processes including bone metabolism, sepsis, cancer, and immunity. In rheumatoid arthritis (RA), fibroblast-...

Descripción completa

Detalles Bibliográficos
Autores principales: Inoue, Takuya, Kohno, Masataka, Nagahara, Hidetake, Murakami, Ken, Sagawa, Tomoya, Kasahara, Akiko, Kaneshita, Shunya, Kida, Takashi, Fujioka, Kazuki, Wada, Makoto, Nakada, Hiroshi, Hla, Timothy, Kawahito, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555509/
https://www.ncbi.nlm.nih.gov/pubmed/31173610
http://dx.doi.org/10.1371/journal.pone.0218090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555509/
https://www.ncbi.nlm.nih.gov/pubmed/31173610
http://dx.doi.org/10.1371/journal.pone.0218090

Ejemplares similares