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Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail

Schwann cells myelinate selected axons in the peripheral nervous system (PNS) and contribute to fast saltatory conduction via the formation of compact myelin, in which water is excluded from between tightly adhered lipid bilayers. Peripheral neuropathies, such as Charcot-Marie-Tooth disease (CMT) an...

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Detalles Bibliográficos
Autores principales: Raasakka, Arne, Ruskamo, Salla, Barker, Robert, Krokengen, Oda C., Vatne, Guro H., Kristiansen, Cecilie K., Hallin, Erik I., Skoda, Maximilian W. A., Bergmann, Ulrich, Wacklin-Knecht, Hanna, Jones, Nykola C., Hoffmann, Søren V., Kursula, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555526/
https://www.ncbi.nlm.nih.gov/pubmed/31173589
http://dx.doi.org/10.1371/journal.pone.0216833