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Blocking tombusvirus replication through the antiviral functions of DDX17-like RH30 DEAD-box helicase

Positive-stranded RNA viruses replicate inside cells and depend on many co-opted cellular factors to complete their infection cycles. To combat viruses, the hosts use conserved restriction factors, such as DEAD-box RNA helicases, which can function as viral RNA sensors or as effectors by blocking RN...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Yu, Nagy, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555533/
https://www.ncbi.nlm.nih.gov/pubmed/31136641
http://dx.doi.org/10.1371/journal.ppat.1007771