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Sparse discriminative latent characteristics for predicting cancer drug sensitivity from genomic features
Drug screening studies typically involve assaying the sensitivity of a range of cancer cell lines across an array of anti-cancer therapeutics. Alongside these sensitivity measurements high dimensional molecular characterizations of the cell lines are typically available, including gene expression, c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555538/ https://www.ncbi.nlm.nih.gov/pubmed/31136571 http://dx.doi.org/10.1371/journal.pcbi.1006743 |