Cargando…

Sparse discriminative latent characteristics for predicting cancer drug sensitivity from genomic features

Drug screening studies typically involve assaying the sensitivity of a range of cancer cell lines across an array of anti-cancer therapeutics. Alongside these sensitivity measurements high dimensional molecular characterizations of the cell lines are typically available, including gene expression, c...

Descripción completa

Detalles Bibliográficos
Autores principales: Knowles, David A., Bouchard, Gina, Plevritis, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555538/
https://www.ncbi.nlm.nih.gov/pubmed/31136571
http://dx.doi.org/10.1371/journal.pcbi.1006743