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Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size

Protein concentration gradients pattern developing organisms and single cells. In Schizosaccharomyces pombe rod-shaped cells, Pom1 kinase forms gradients with maxima at cell poles. Pom1 controls the timing of mitotic entry by inhibiting Cdr2, which forms stable membrane-associated nodes at mid-cell....

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Detalles Bibliográficos
Autores principales: Gerganova, Veneta, Floderer, Charlotte, Archetti, Anna, Michon, Laetitia, Carlini, Lina, Reichler, Thais, Manley, Suliana, Martin, Sophie G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555594/
https://www.ncbi.nlm.nih.gov/pubmed/31050340
http://dx.doi.org/10.7554/eLife.45983