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How I treat MSI cancers with advanced disease

Mismatch repair deficiency (dMMR) results in microsatellite instability (MSI) and is strongly associated with responsiveness to programmed death-1 receptor (PD-1)-blocking antibodies. Probably the main driver for the observed high efficacy of immune checkpoint inhibitors in dMMR tumours is the remar...

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Detalles Bibliográficos
Autores principales: Kok, Marleen, Chalabi, Myriam, Haanen, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555602/
https://www.ncbi.nlm.nih.gov/pubmed/31231574
http://dx.doi.org/10.1136/esmoopen-2019-000511