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Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina

BACKGROUND: Microglia and inflammation have context-specific impacts upon neuronal survival in different models of central nervous system (CNS) disease. Herein, we investigate how inflammatory mediators, including microglia, interleukin 1 beta (IL1β), and signaling through interleukin 1 receptor typ...

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Detalles Bibliográficos
Autores principales: Todd, Levi, Palazzo, Isabella, Suarez, Lilianna, Liu, Xiaoyu, Volkov, Leo, Hoang, Thanh V., Campbell, Warren A., Blackshaw, Seth, Quan, Ning, Fischer, Andy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555727/
https://www.ncbi.nlm.nih.gov/pubmed/31170999
http://dx.doi.org/10.1186/s12974-019-1505-5