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Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina

BACKGROUND: Microglia and inflammation have context-specific impacts upon neuronal survival in different models of central nervous system (CNS) disease. Herein, we investigate how inflammatory mediators, including microglia, interleukin 1 beta (IL1β), and signaling through interleukin 1 receptor typ...

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Detalles Bibliográficos
Autores principales:	Todd, Levi, Palazzo, Isabella, Suarez, Lilianna, Liu, Xiaoyu, Volkov, Leo, Hoang, Thanh V., Campbell, Warren A., Blackshaw, Seth, Quan, Ning, Fischer, Andy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555727/ https://www.ncbi.nlm.nih.gov/pubmed/31170999 http://dx.doi.org/10.1186/s12974-019-1505-5

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