Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice

BACKGROUND: As reported previously by our group, medium-chain triglycerides can ameliorate atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized herein that caprylic acid (C8:0) would suppress inflammation via TLR4/NF-κB signaling and further promote the amelioratio...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xinsheng, Xue, Changyong, Xu, Qing, Zhang, Yong, Li, Huizi, Li, Feng, Liu, Yinghua, Guo, Changjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555760/
https://www.ncbi.nlm.nih.gov/pubmed/31182969
http://dx.doi.org/10.1186/s12986-019-0359-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555760/
https://www.ncbi.nlm.nih.gov/pubmed/31182969
http://dx.doi.org/10.1186/s12986-019-0359-2

Ejemplares similares