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Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice
BACKGROUND: As reported previously by our group, medium-chain triglycerides can ameliorate atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized herein that caprylic acid (C8:0) would suppress inflammation via TLR4/NF-κB signaling and further promote the amelioratio...
Autores principales: | Zhang, Xinsheng, Xue, Changyong, Xu, Qing, Zhang, Yong, Li, Huizi, Li, Feng, Liu, Yinghua, Guo, Changjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555760/ https://www.ncbi.nlm.nih.gov/pubmed/31182969 http://dx.doi.org/10.1186/s12986-019-0359-2 |
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