Axonal Protection by Tacrolimus with Inhibition of NFATc1 in TNF-Induced Optic Nerve Degeneration

Tacrolimus, a calcineurin (CaN) inhibitor, has been used for treatment of refractory allergic ocular disease, although its role in optic nerve degeneration remains to be elucidated. In this study, we investigated whether tacrolimus modulates tumor necrosis factor (TNF)-mediated axonal degeneration a...

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Detalles Bibliográficos
Autores principales: Tsukahara, Chihiro, Sase, Kana, Fujita, Naoki, Takagi, Hitoshi, Kitaoka, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555779/
https://www.ncbi.nlm.nih.gov/pubmed/31087207
http://dx.doi.org/10.1007/s11064-019-02804-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555779/
https://www.ncbi.nlm.nih.gov/pubmed/31087207
http://dx.doi.org/10.1007/s11064-019-02804-6

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