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Exploration of interaction scoring criteria in the CANDO platform

OBJECTIVE: Ascertain the optimal interaction scoring criteria for the Computational Analysis of Novel Drug Opportunities (CANDO) platform for shotgun drug repurposing to improve benchmarking performance, thereby enabling more accurate prediction of novel therapeutic drug-indication pairs. RESULTS: W...

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Detalles Bibliográficos
Autores principales: Falls, Zackary, Mangione, William, Schuler, James, Samudrala, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555930/
https://www.ncbi.nlm.nih.gov/pubmed/31174591
http://dx.doi.org/10.1186/s13104-019-4356-3