CD45RA(+)CCR7(−) CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab

BACKGROUND: Checkpoint inhibitors have become standard care of treatment for non-small cell lung cancer (NSCLC), yet only a limited fraction of patients experiences durable clinical benefit, highlighting the need for markers to stratify patient populations. METHODS: To prospectively identify patient...

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Detalles Bibliográficos
Autores principales: Kunert, Andre, Basak, Edwin A., Hurkmans, Daan P., Balcioglu, Hayri E., Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid A. M., Lamers, Cor H. J., Bins, Sander, Koolen, Stijn L. W., van der Veldt, Astrid A. M., Sleijfer, Stefan, Mathijssen, Ron H. J., Aerts, Joachim G. J. V., Debets, Reno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555948/
https://www.ncbi.nlm.nih.gov/pubmed/31176366
http://dx.doi.org/10.1186/s40425-019-0608-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555948/
https://www.ncbi.nlm.nih.gov/pubmed/31176366
http://dx.doi.org/10.1186/s40425-019-0608-y

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