Nek2B activates the wnt pathway and promotes triple-negative breast cancer chemothezrapy-resistance by stabilizing β-catenin

BACKGROUND: The chemotherapy-resistance of triple-negative breast cancer (TNBC) remains a major challenge. The Nek2B kinase and β-catenin serve as crucial regulators of mitotic processes. The aim of this study was to test the correlation between Nek2B and TNBC chemotherapy sensitivity, and to determ...

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Detalles Bibliográficos
Autores principales: Shen, Honghong, Yan, Wenpeng, Yuan, Jinyang, Wang, Ziyue, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556028/
https://www.ncbi.nlm.nih.gov/pubmed/31174562
http://dx.doi.org/10.1186/s13046-019-1231-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556028/
https://www.ncbi.nlm.nih.gov/pubmed/31174562
http://dx.doi.org/10.1186/s13046-019-1231-y

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