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Nek2B activates the wnt pathway and promotes triple-negative breast cancer chemothezrapy-resistance by stabilizing β-catenin

BACKGROUND: The chemotherapy-resistance of triple-negative breast cancer (TNBC) remains a major challenge. The Nek2B kinase and β-catenin serve as crucial regulators of mitotic processes. The aim of this study was to test the correlation between Nek2B and TNBC chemotherapy sensitivity, and to determ...

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Detalles Bibliográficos
Autores principales:	Shen, Honghong, Yan, Wenpeng, Yuan, Jinyang, Wang, Ziyue, Wang, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556028/ https://www.ncbi.nlm.nih.gov/pubmed/31174562 http://dx.doi.org/10.1186/s13046-019-1231-y

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