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DNA damage repair gene mutations and their association with tumor immune regulatory gene expression in muscle invasive bladder cancer subtypes

BACKGROUND: Molecular subtyping of urothelial cancer (UC) has significantly advanced the understanding of bladder tumor heterogeneity and development of prognostic and predictive biomarkers. Evolving evidence across cancers strongly suggests that tumor immunoediting has a profound impact on the beha...

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Detalles Bibliográficos
Autores principales: Vidotto, Thiago, Nersesian, Sarah, Graham, Charles, Siemens, D. Robert, Koti, Madhuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556053/
https://www.ncbi.nlm.nih.gov/pubmed/31174611
http://dx.doi.org/10.1186/s40425-019-0619-8