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Structural and Functional Determinants of AC8 Trafficking, Targeting and Responsiveness in Lipid Raft Microdomains

The fidelity of cAMP in controlling numerous cellular functions rests crucially on the precise organization of cAMP microdomains that are sustained by the scaffolding properties of adenylyl cyclase. Earlier studies suggested that AC8 enriches in lipid rafts where it interacts with cytoskeletal eleme...

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Detalles Bibliográficos
Autores principales: Tabbasum, Valentina G., Cooper, Dermot M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556161/
https://www.ncbi.nlm.nih.gov/pubmed/30746562
http://dx.doi.org/10.1007/s00232-019-00060-x