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Effect of permeation enhancers on in vitro release and transdermal delivery of lamotrigine from Eudragit(®)RS100 polymer matrix-type drug in adhesive patches

The drug-in-adhesive (DIA)-type matrix patches of lamotrigine are developed using variable permeation enhancers (oleic acid, PG, lemon oil and aloe vera), and drug in vitro release and its permeation are evaluated. Lamotrigine has been long used as an anti-epileptic, mood stabilizer, to treat bipola...

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Detalles Bibliográficos
Autores principales: Jafri, Ifrah, Shoaib, Muhammad Harris, Yousuf, Rabia Ismail, Ali, Fatima Ramzan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556165/
https://www.ncbi.nlm.nih.gov/pubmed/31069700
http://dx.doi.org/10.1007/s40204-019-0114-9