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Raddeanin A Induces Apoptosis and Cycle Arrest in Human HCT116 Cells through PI3K/AKT Pathway Regulation In Vitro and In Vivo

This study aimed to investigate the in vitro and in vivo effects of Raddeanin A on apoptosis and the cell cycle in the human colorectal cell line, HCT116, and to explore the possible underlying mechanisms of action. We found the growth inhibition rate gradually increased as the drug concentration in...

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Detalles Bibliográficos
Autores principales: Meng, Chunqin, Teng, Yuhao, Jiang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556300/
https://www.ncbi.nlm.nih.gov/pubmed/31239864
http://dx.doi.org/10.1155/2019/7457105