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Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells

Renal inflammation can result in renal injury. Uric acid (UA) is the final product of purine metabolism in humans and because of the lack of urate oxidase, UA may accumulate in tissues, including kidney, causing inflammation. Galangin was isolated from a traditional Chinese medicine plant and posses...

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Detalles Bibliográficos
Autores principales: Lu, Hao, Yao, Hui, Zou, Rong, Chen, Xiwen, Xu, Hanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556363/
https://www.ncbi.nlm.nih.gov/pubmed/31240210
http://dx.doi.org/10.1155/2019/3018357